鏈涙湀鐩存挱app涓嬭浇鏈€鏂扮増鏈?鏈涙湀鐩存挱app涓嬭浇鏈€鏂扮増鏈笅杞藉湴鍧€-凯时登录

鏈涙湀鐩存挱app涓嬭浇鏈€鏂扮増鏈帿鏂甯傞暱锛氳帿鏂鍙兘鍑虹幇浜嗘柊鐨勫彉寮傛瘨鏍?/span>涔屽厠鍏版斂搴滆в闄ゆ潵鑷嵃搴︾殑澶栫睄浜哄＋鍏ュ绂佷护

1.浣嗗鍏跺畠n-of-1鑽墿鐨勬瘨鎬ф楠岋紝涓嶄細鎬讳細鍍弇ilasen鑽墿杩欐牱涓€甯嗛椤恒€傚綋澶у瀵逛竴绉嶇枟娉曞叿浣撶殑鐢熺墿鍒嗗竷鐭ヤ箣鐢氬皯鏃讹紝鍙兘闇€瑕佸紑灞曟洿骞挎硾鐨勭爺绌躲€備絾涓婅堪渚嬪瓙锛岃〃鏄庝簡姣掔悊瀛︾爺绌剁殑鏃堕棿琛ㄥ拰瑕佹眰锛屽彲浠ユ湁寰堝ぇ鐨勭伒娲绘€с€侭lack鍗氬＋琛ㄧず锛屼负姝ゅ垱涓嬩簡濂藉嚑涓厛渚嬶紝濂瑰笇鏈涳紝杩欎簺鍏堜緥鑳藉缁忓緱浣忔楠屻€傘€愯嵂鍝佺爺鍙戙€?/dl>

2.浠庣敓鐗╁埗鍝佽嵂鍝佹暟閲忕湅锛屽叡39涓嵂鐗╋紝鐤嫍浜у搧鍏辫32涓紝鍗犳瘮82%锛屽叾浣欎负鎶椾綋鍜岄噸缁勮泲鐧借嵂鍝併€傚浘42016鈥?019骞存姉鐥呮瘨鑽墿涓敓鐗╁埗鍝佺被鍨嬪垎鏋怱angamo鏈€鏈夊悕鐨勫熀鍥犵粍璋冩帶鎶€鏈€斺€旈攲鎸囪泲鐧借浆褰曞洜瀛愶紙zfp-tf锛夛紝鏄皢aavs鍙婃惡甯︾殑鐗瑰畾鍔熻兘閫掗€佸埌dna涓婏紝鍏堕€夋嫨鎬у湴闃婚亸鎴栨縺娲荤壒瀹氬熀鍥犵殑琛ㄨ揪锛屼互瀹炵幇娌荤枟鏁堟灉銆備复搴婂墠鐮旂┒鏄剧ず锛屼娇鐢ˋav杞戒綋閫掗€侀澏鍚憈au铔嬬櫧鐨凷t-501鍜岄澏鍚懳辩獊瑙︽牳铔嬬櫧st-502鐨刏fp-tf锛屽tau铔嬬櫧鍜屛辩獊瑙︽牳铔嬬櫧鍏锋湁楂樺害鐗瑰紓鎬с€佹湁鏁堟€у拰鍙皟鑺傜殑鎶戝埗浣滅敤銆?/dl>

3.2鏈圕de鍏辨壙鍔?8涓搧绉嶇殑浠垮埗鐢宠锛屽叾涓寜3绫荤敵鎶ョ殑鍝佺鏈?5涓紝鎸?绫荤敵鎶ョ殑鍝佺鏈?3涓紝21涓搧绉嶇洰鍓嶅凡鏈変紒涓氶€氳繃鎴栬鍚岄€氳繃涓€鑷存€ц瘎浠凤紝10涓搧绉嶄负棣栧浼佷笟鎻愪氦浠垮埗鐢宠锛岃缁嗘儏鍐佃瑙佷笅琛細鐟炲痉璧涢煢鏄疓ileadsciences閽堝2014骞磋タ闈炲焹鍗氭媺鐥呮瘨鐤儏寮€鍙戠殑涓€绉嶈嵂鐗╋紝浠婂勾鏃╀簺鏃跺€欏湪缇庡浗棣栨鐢ㄤ簬娌荤枟涓€鍚嶆柊鍨嬪啝鐘剁梾姣掓偅鑰呫€?/dl>

4.[1]esperionannouncesfdaapprovalofthenexlizet?(bempedoicacidandezetimibe)tablet,anoral,once-daily,non-statinldl-cholesterolloweringmedicine,retrievedfebruary27,2020,fromhttps://www.esperion.com/investors-media/press-releases/鍘熸爣棰橈細浠庢柊鍐犺偤鐐庢不鐤楃湅鎴戝浗鐥呮瘨绉戠爺鐨勭幇鐘朵笌瓒嬪娍*澹版槑锛氭湰鏂囩敱鍏ラ┗鏂版氮鍖昏嵂鏂伴椈浣滆€呮挵鍐欙紝瑙傜偣浠呬唬琛ㄤ綔鑰呮湰浜猴紝涓嶄唬琛ㄦ柊娴尰鑽柊闂荤珛鍦恒€?/dl>

5.璺槑鍏嬫柉鍏徃瀹ｅ竷锛岃鍏徃宸茬粡鍚戠編鍥介鍝佽嵂鍝佺洃鐫ｇ鐞嗗眬鎻愪氦浜嗚verigene®ii鍛煎惛閬揊lex璇曞墏鐩掕幏寰?10(k)鎵瑰噯鐨勭敵璇凤紝杩欐槸鍚慒da鎻愪氦鐢宠鐨勭浜屾verigeneii璇曞墏鐩掋€備笘鍗粍缁囨€诲共浜嬭碍寰峰姝ゅ墠琛ㄧず锛岀洰鍓嶏紝鍙ｇ僵绛変釜浜洪槻鎶ょ敤鍝佺殑闇€姹傞噺鏄甯告按骞崇殑100鍊嶏紝浠锋牸鍒欐槸姝ｅ父姘村钩鐨?0鍊嶃€?/dl>

6.鎸夌収涓€骞存不鐤楄垂鐢ㄧ殑鎬讳环鏉ョ湅锛岀櫨娴庣宸炵殑鐧炬辰瀹夊勾娌荤枟璐圭敤鏈€浣庣害涓?0.69涓囧厓锛岃€屼俊杈剧敓鐗╃殑杈句集鑸掑拰鍚涘疄鐢熺墿鐨勬嫇鐩婂垯鍒嗗埆涓?0.23涓囧厓鍜?0.08涓囧厓銆傚鎵规儏鍐碉細2011骞磋幏寰桟e璁よ瘉锛?014骞磋幏寰桭da鎵瑰噯銆?/dl>

1.鈥滈偅鍑犲勾澶柉鐙備簡锛佲€?鏁涜储2浜跨殑澶勭骇瀹樺憳鏇炬槸3涓€滆€佽檸鈥濈殑涓嬪睘

2.鍗堢洏锛氱編鑲＄淮鎸佽穼鍔?閬撴寚鍙兘杩炶穼浜旀棩

3.鏂拌兘婧愯溅鏉垮潡閫犲ソ锛岀悊鎯虫苯杞︽定瓒?0%锛屽皬楣忔苯杞︽定瓒?%

4.銆€銆€缇庡浗鍥藉鑸┖鑸ぉ灞€绁濊春绁炶垷鍗佷簩鍙疯浇浜洪鑸规垚鍔熷彂灏?/dl>

5.鏋楅儜鏈堝ē锛氶娓粡娴庢洐鍏夋笎瑙?/dl>

6.閲嶇锛佸浗鍔￠櫌甯稿姟浼氳鍐冲畾锛氬瀹為檯绉嶇伯鍐滄皯涓€娆℃€у彂鏀捐ˉ璐达紒

鎺ㄨ崘鍔熻兘

1.閴翠簬hemlibra鍦ㄤ綋鍐呮棤鎶戝埗鍓傜殑鎴愬勾鎮ｈ€呬腑鐨勬壒閲忛噰璐环鏍煎湪姣忓勾60涓囩編鍏冭嚦80涓囩編鍏冧箣闂达紝biomarin鐨勯璁″畾浠峰湪100涓囩編鍏冭嚦500涓囩編鍏冧箣闂淬€傜敱浜庡埌涓婂競鏃跺皢浼氭湁鍥涘勾澶氱殑valrox鐨勬暟鎹紝浠锋牸鍙互瀹氫负hemlibra骞冲潎浠锋牸锛?00,000缇庡厓锛夌殑鍥涘€嶏紝纭畾鍦?80涓囩編鍏冦€傝繖灏嗕娇鍏舵垚涓烘渶鏄傝吹鐨勪竴娆℃€х枟娉曪紝瓒呰繃璇哄崕鍏徃鐨勮剨楂撴€ц倢钀庣缉鍩哄洜鐤楁硶zolgensma锛坥nasemnogeneabeparvovec-xioi锛?10涓囩編鍏冪殑浠锋牸銆傝鍏徃琛ㄧず锛岃繖鏄拡瀵硅鍙嬬梾鐨勭涓€娆惧熀鍥犵枟娉曪紝瀵逛竴浣嶅吀鍨嬫偅鑰呯殑涓€鐢熺殑璐圭敤灏嗕細涓哄尰鐤椾繚鍋ョ郴缁熻妭鐪佽秴杩?000涓囩編鍏冦€侻orrow璇达細鈥滈暱鏈熸潵鐪嬶紝鎴戜滑甯屾湜鑳藉璇卞鍐呮簮鎬х缁忓共缁嗚優鏉ュ府鍔╀腑椋庢垨鍏跺畠绫诲瀷绁炵粡鐥呭彉鍚庣殑缁勭粐鍐嶇敓銆傗€?/dl>

2.鏂板姞鍧★細鏁板妯″瀷鎻ず楂樻晥鐨勯殧绂诲拰杩借釜濡備綍璧蜂綔鐢ㄦ柊鍐犵柅鎯呭嚭鐜颁互鏉ワ紝鍏ㄤ笘鐣岀浉缁ф湁60澶氫釜鍥藉鍙楀埌褰卞搷銆傚湪涓ユ牸鐨勭鎺ф帾鏂戒笅锛岀柅鎯呭湪鎴戝浗宸插緱鍒板垵姝ユ帶鍒讹紝鐜板瓨纭瘖鐥呬緥鏁颁笉鏂笅闄嶃€備笉杩囷紝褰撲腑鍥界殑闃叉帶鐤儏鎺柦鍙楀埌涓栧崼缁勭粐绉拌禐涔嬫椂锛岃繕鏈変竴涓浗瀹朵篃鍥犲叾鍦ㄩ槻鎺х柅鎯呮柟闈㈢殑涓炬帾鑰屽彈鍒颁笘鐣岀灘鐩紝瀹冨氨鏄柊鍔犲潯銆傦紙2锛夊嚒鏍囧織鏈夋敹璐€佸嚭鍞叏铦庡甫鏈夆€滈噹鐢熲€濅簩瀛楋紝涓€寰嬫寜鐓ф硶寰嬭瀹氫簣浠ユ敹缂淬€?/dl>

3.浜哄姏璧勬簮绀句細淇濋殰閮ㄧ淮鏇硷細鎬ユ晳鍛煎惛鏈?杞繍鍛煎惛鏈恒€侀櫎棰や华绛夈€?/dl>

4.瑗块棬瀛愶細鍖荤枟杞︺€佹柟鑸憋紙ct銆丏r锛夌瓑锛?鏈?8鏃ュ浗鍔￠櫌鑱旈槻鑱旀帶鏈哄埗鏂伴椈鍙戝竷浼氫笂锛屽浗瀹跺崼鍋ュ鍥炲簲绉帮紝鍚勫湴瀵瑰嚭闄㈡偅鑰呰繘琛岃窡韪殢璁垮拰鍋ュ悍绠＄悊锛岄€氳繃鐩戞祴鍙戠幇锛屽嚭闄⑩€滃闃斥€濇偅鑰呮病鏈夊啀鍙戠敓浼犳煋鍒汉鐨勭幇璞★紝鏈変竴閮ㄥ垎鎮ｈ€呭啀妫€娴嬫椂鍙堣浆涓洪槾鎬с€傛柊鍐犺偤鐐庣梾姣掓槸涓€涓柊鐥呮瘨锛屽畠鐨勮嚧鐥呮満鐞嗐€佺柧鐥呯殑鍏ㄨ矊鍜岀梾绋嬬殑鐗圭偣閮借繕闇€瑕佽繘涓€姝ョ殑鍔犳繁璁よ瘑銆?/dl>

5.娴峰崡鐪佸皢鍗忚皟銆侀紦鍔遍€氫俊杩愯惀鍟嗗鎻村姪婀栧寳鍖诲姟浜哄憳缁欎簣姣忎汉姣忔湀閫氫俊璐硅ˉ鍔?00鍏冦€傝涓氫粠涓氳€呮寚鍑猴紝鍘嬫车涓庡柗闆炬定浠锋渶鍘夊锛屽帇娉典粠骞虫椂0.4鍏冩定鍒?.9鍏冿紝鍠烽浘澶村钩鏃舵墠3姣涢挶锛岀幇鍦ㄧ倰鍒颁簡1.6鍏冿紝浠ュ墠涓€涓?00ml鐨凱et鐡?鍠峰ご鏁翠綋浠锋牸绾?鍏冿紝鐜板湪鍙兘涓€涓柗澶村氨瑕?鍏冦€?/dl>

搴旂敤搴旂敤

1銆佸紶涓€涓癸紙鍖栧悕锛夌殑鐖朵翰琚‘璇婃牳閰搁槼鎬э紝铏界劧鏈夎偤姘旇偪绛夊熀纭€鐤剧梾锛岃繕鏄绀惧尯鎺ㄨ崘杩涗簡鏂硅埍锛屼絾浠栨槸鍦ㄧ瓑寰呭尰闄㈠簥浣嶆棤鏈涚殑鎯呭喌涓嬫棤濂堝幓鏂硅埍鐨勩€傜煭鐭嚑澶╁唴寤虹珛鐨勬柟鑸憋紝寮€濮嬫帴鏀剁梾浜烘椂鍩虹鏉′欢骞朵笉濂斤紝鐘圭枒鐨勭梾浜轰笉婊＄殑鎯呯华寰堝鏄撹鐐圭噧銆傛嵁涓€浣嶆柟鑸卞尰闄㈠尰鐢熷洖蹇嗭細鈥?鏈?鍙锋櫄涓婄涓€娆℃敹鐥呬汉锛岀浉褰撲簬涓€杈规寲鎴樺锛屼竴杈规墦闃诲嚮鎴樸€傗€濇椽灞变綋鑲查鏂硅埍鍖婚櫌鍦ㄦ敹鐥呬汉褰撳ぉ锛岀梾浜轰笉婊℃剰鎻掓澘娌℃湁鐢点€侀鐗╁拰鏆栨皵锛屾儏缁け鎺э紝鎶ゅ＋瀹夋姎浜嗗緢涔呫€?020骞?鏈?0鏃ワ紝鐑櫙鐢熺墿閽堝鏂板瀷鍐犵姸鐥呮瘨鍏嶇柅蹇€熻瘯鍓傚拰閰跺厤璇曞墏鍏堝悗鐮斿彂鎴愬姛銆?/dt>

2銆?鏈?6鏃ワ紝nmpa瀹樼綉鍏竷2020骞?2鏈?6鏃ヨ嵂鍝佹壒浠跺彂甯冮€氱煡锛屽鍙楃灘鐩殑姝ｅぇ澶╂櫞鍚稿叆鐢ㄥ竷鍦板寰锋贩鎮恫鎷垮埌鑽搧鎵逛欢锛屾寮忚幏鎵广€傚湪鍚堣鏃ヨ秼鍏夋槑鍖栫殑浠婂ぉ锛屼笉浠呮湁鏀垮簻閮ㄩ棬鐩存帴鐩戠锛岃繕鏈夐洦鍚庢槬绗嬭埇鐨勬斂绛栧奖鍝嶃€傝繖浜涙斂绛栫湅璧锋潵璺熷悎瑙勮储鍔℃病鏈変粈涔堝緢澶х殑鍏崇郴锛屼絾杩欐槸闅愬舰鐨勮蒋鍔涢噺锛屾瘮濡傗€滀袱绁ㄥ埗鈥濄€佲€滃甫閲忛噰璐€濄€佲€滃尰淇濊皥鍒も€濄€傛槑鏄炬槸鍥藉宸茬粡閲囧彇鐩戠鍔犳斂绛栨潵瑙勮寖澶у鐨勫悎瑙勮涓轰簡銆?/dt>

3銆佸埄鐢?018骞碅杞拰b杞瀺璧勭闆嗙殑3.3浜跨編鍏冧互鍙奍po鎵€寰楋紝gossamer灏嗘帹鍔ㄥ叾涓変釜鍏抽敭涓村簥璧勪骇锛氬彛鏈嶅墠鍒楄吅绱燚2鍙椾綋2鎷姉鍓侴b001锛屾不鐤椾腑閲嶅害鍡滈吀鎬х矑缁嗚優鎬у摦鍠樸€佹參鎬ч蓟绐︾値鍜屾參鎬ц嚜鍙戞€ц崹楹荤柟锛堝潎澶勪簬2鏈熶复搴婏級锛涘惛鍏ユ€ц灏忔澘琛嶇敓鐨勭敓闀垮洜瀛愬彈浣撴縺閰舵姂鍒跺墏gb002锛屾不鐤楄偤鍔ㄨ剦楂樺帇锛堝浜?鏈熶复搴婏級锛涗綆姘ц瀵煎洜瀛?1a绋冲畾鍓侴b-004锛屾不鐤楃値鐥囨€ц偁鐥咃紙澶勪簬1鏈熶复搴婏級銆?019骞?1鏈堬紝gossamer涓庨粯娌欎笢鍚堜綔锛岃瘎浼癴irst-in-class鍙ｆ湇cd11b璋冭妭鍓侴b1275涓庢鏌ョ偣鎶戝埗鍓侹eytruda鑱斿悎娌荤枟鏌愪簺鏅氭湡瀹炰綋鐦ゆ偅鑰呫€傚熀浜庡競鍦轰富浣撳叿鏈変竴瀹氱爺鍙戝姩鍔涳紝浣嗗垱鏂版姇鍏ヤ笉瓒充笉鎸佺画鍙婇珮鏍＄鐮旀満鏋勭粡璐逛繚闅滀笉绋冲畾绛夐棶棰橈紝涓烘彁鍗囧簲瀵逛紶鏌撶梾鐤儏鐨勫簲鎬ヨ兘鍔涳紝骞舵帹鍔ㄧ柅鎯呮湡闂翠紬澶氱鐮旀垚鏋滆兘澶熷疄鐜版湁鏁堣浆鍖栵紝鎴戝浗棰勮浼氫粠濡備笅鍑犱釜鏂归潰淇濋殰鎶楃梾姣掔鐮旂殑鍙寔缁€э紝涓€鏄鍥藉鍌ㄥ鐨勬姉鍑讳紶鏌撶梾鑽墿鐮斿彂缁欎簣璧勯噾鏀寔锛岄紦鍔辨湁鑽墿鐮斿彂鍩虹鐨勫埗鑽紒涓氫粠浜嬫姉鍑讳紶鏌撶梾鐩稿叧鑽墿鐨勭爺鍙戙€備簩鏄紦鍔遍珮鏍″拰鐮旂┒鏈烘瀯鐨勭梾姣掔爺绌讹紝寮曞淇冭繘绉戝鐮旂┒搴旂敤钀藉湴锛岄紦鍔辨姉鐥呮瘨鑽墿鐨勫墠娌跨爺鍙戙€備笁鏄紦鍔辩鐮斾笌鍒惰嵂浜т笟鍗忓悓鍚堜綔锛屽缓绔嬪畬鏁翠骇涓氶摼锛屼績杩涙姉鐥呮瘨鑽墿鐮斿彂鐨勪骇涓氬寲钀藉湴銆傚洓鏄€氳繃鐩稿叧閲嶅ぇ涓撻」锛屼績浣垮埗鑽紒涓氭姇鍏ユ姉鐥呮瘨鑽墿鐨勫熀纭€鐮旂┒涓庝骇涓氬寲锛屾敮鎸佷紶鏌撶梾鑽墿鐨勪复搴婄爺绌躲€備簲鏄缓绔嬩紶鏌撶梾鑽墿鐗规畩瀹¤瘎瀹℃壒閫氶亾锛屽姞閫熺浉鍏宠嵂鐗╃爺鍙戙€?/dt>

4銆侀紦鍔变緷鎵樺尯鍩熷崼鐢熷仴搴蜂簯骞冲彴瀹炵幇闅忚鏁版嵁鐨勮仈閫氫笌鍏变韩銆傚搴尰鐢熸湇鍔″洟闃熻涓诲姩鍏冲績绛剧害灞呮皯锛屾帹閫侀拡瀵规€с€佷釜鎬у寲鐨勫仴搴锋暀鑲插拰鐤儏闃叉帶淇℃伅锛屾彁渚涘仴搴峰鏁欐湇鍔★紝鎸囧绛剧害灞呮皯寮€灞曡嚜鎴戝仴搴风鐞嗕笌涓汉闃叉姢锛岃繘涓€姝ユ彁鍗囩绾﹀眳姘戝瀹跺涵鍖荤敓绛剧害鏈嶅姟鐨勬弧鎰忓害涓庤幏寰楁劅銆傚弬鑰冭祫鏂欙細

5銆丷t-lamp63掳c涓嬫俯鑲?0鍒嗛挓鍙幏鏈€浣虫墿澧炵粨鏋滀絾鍖栫枟浠嶆槸鐩墠鏈€骞挎硾鐢ㄤ簬娌荤枟鏂扮‘璇奵hl鎮ｈ€呯殑鏂规銆備复搴婁笓瀹舵浘琛ㄧず锛屼笉纭俊璇曢獙鏁版嵁鑳芥樉绀篈dcetris杈冨寲鐤楀叿鏈夊己澶х殑鐤楁晥浼樺娍銆侫dcetris鍦ㄧ編鍥藉拰鍔犳嬁澶х殑2019骞寸鍥涘搴﹂攢鍞涓?.662浜跨編鍏冿紝浣庝簬鍗庡皵琛楅鏈熺殑1.745浜跨編鍏冿紝杩欎篃琛ㄦ槑涓村簥浣跨敤璇ヤ骇鍝佺殑閫熷害浣庝簬棰勬湡銆?/dt>

鏃х増鐗硅壊

銆€銆€骞夸笢涓滆帪灏嗗紑灞曟秹鍙婄害250涓囦汉鏍搁吀妫€娴嬪伐浣?棰勮6鏈?9鏃ュ嚭妫€娴嬬粨鏋?/dt>

鐚滀綘鍠滄

鏈涙湀鐩存挱app涓嬭浇鏈€鏂扮増鏈?/p>

• 绂忓埄

  (57315/89958kb / 1970-01-01)

• 璐㈢粡

  (24889/60969kb / 1970-01-01)

• 鍥介檯

  (53666/20838kb / 1970-01-01)

• 鐭ラ亾

  (75061/81277kb / 1970-01-01)

• 鍥介槻

  (92239/61407kb / 1970-01-01)

• 鍐涗簨

  (45433/03428kb / 1970-01-01)

鐩稿叧鏀荤暐

鐩稿叧鏂伴椈